The driver of a four-door pickup turned right at the main intersection at Phuket City's Saphan Hin park about 10pm and collided with a speeding motorcycle, carrying two youths.
A large crowd was in the vicinity. One of the youths on the pink and white Scoopi motorcycle suffered serious injuries.
The driver of the pickup turned right from Phuket Road into Bangyai Road, near Phuket Vocational College, then hit the motorcycle.
The youths were taken to Vachira Phuket Hospital where one was admitted with a broken arm.
Earlier at 11am, a covered pickup carrying a 44-gallon drum of diesel fuel from Patong to Phuket City lost control on a bend in Phra Phuket Keaw Road near the Tesco Lotus intersection and crashed into a motorcycle.
The rider of the motorcycle, Darat Teankamnard, 48, was taken to Vachira Phuket Hospital where she was admitted.